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Job Record #16743
TitlePostdoc in Fluid-structure modeling of embryonic development
CategoryPostDoc Position
EmployerUniversity of Texas Southwestern Medical Center
LocationUnited States, Texas, Dallas
InternationalYes, international applications are welcome
Closure Date* None *

The work in the Doubrovinski laboratory is focused on uncovering the physical 
aspects of animal development. Using fruit fly (Drosophila melanogaster) 
embryo as an experimental model, we have developed a tool box of experimental 
techniques that allow measuring rheological properties of embryonic tissues 
directly in a living developing fly embryo. Our work has revealed that the 
embryonic cell consists of viscous interior (cytoplasm) enclosed by a highly 
elastic cell surface (cellular cortex). Careful quantitative measurements 
have allowed us to determine material parameters characterizing those 
cellular compartments. Currently, our research is focused on utilizing the 
information acquired in quantitative in vivo measurements of tissue rheology 
to understand endogenous tissue movements that shape an embryo during 

Project description:

We are looking for an expert in computational fluid dynamics to model tissue 
dynamics during embryonic development. The project will involve developing 
simulations of embryonic tissue dynamics occurring during the development of 
a fruit fly embryo. The models developed will be rigorously tested using a 
variety of biological experiments (fly genetics, microscopy, laser ablation, 
etc.) so we are looking for someone who is eager to collaborate with 
experimentalists in the lab. This project is a continuation of an ongoing 
collaboration with the Mandadapu group at UC Berkeley, and the work will be 
co-advised by Kranthi Mandadapu.


We require some familiarity with computational fluid dynamics. Expertise in 
fluid-structure interactions, finite element analysis, and experience with 
parallelization (in particular GPU) is desirable (though none of the above is 
an absolute requirement).
Contact Information:
Please mention the CFD Jobs Database, record #16743 when responding to this ad.
NameKonstantin Doubrovinski
Email ApplicationYes
AddressThe Green Center for Systems Biology
UT Southwestern Medical Center, ND11.300
6001 Forest Park Blvd.
Dallas, TX 75390-8597
Record Data:
Last Modified22:56:54, Sunday, September 13, 2020

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