While checking the volume mesh for complicated part, GAMBIT shows

"Total of 10 highly skewed elements encountered.

1 out of 1 meshed volume failed mesh check for skewed elements(equisize skew > 0.97)

0 out of 1 meshed volume failed mesh check for inverted elements"

(total mesh volumes are 482970)

Please let me know how to solve this problem. Can highly skewed elements create problem later in the analysis? (though there is no negative volume)

Please...please reply as early as possible.

Thanks in advance.

yes but you can run with up to 0.99. It depends on where they are and how severely skewed. You may be able to convert skewed cells to polyhedra inside Fluent which will get around them. But Id look at it in Gambit/TGrid and try to remesh the surface or smooth/swap to improve face skewness which should be <0.75-0.8.