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Modeling a filter for living cell separation

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Old   September 4, 2024, 10:59
Exclamation Modeling a filter for living cell separation
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Basak Erkek
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Hello,

I use a track-etched membrane for cancer cell separation in my experiments. I am trying to model a filter for cancer cell separation to determine experiment parameters.

As you guessed, the filter has too many pores on the surface. I used the "porous media" interface under the laminar flow module instead of modeling pore geometry to dispose of enormous computing power. Yet, I checked the literature, and "porous media" may be used for different purposes such as modeling riverbanks, etc.

Also, in my filter model, the filter has the smallest hydraulic resistance when I compared with the other fluidic channels. According to my calculations and even logically, the filter should have the biggest resistance on the system. As a result, I have a big problem!

Could you help me?

Best regards,

Basak
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cancer cell, comsol, filter, porous media


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