Postdoctoral Researcher in Biophysics

A postdoctoral training position at the interface of Biophysics and 
Developmental Biology is available in the laboratory of Konstantin Doubrovinski, 
at UT Southwestern Medical Center, in collaboration with Dr. Weria Pezeshkian 
(University of Copenhagen). Our laboratory has been establishing unique 
measurement tools to probe cells and their constituents in developing embryos, 
with the aim of systematically mapping out material properties of cellular 
structures. The work focuses on uncovering the physical basis of tissue dynamics 
in the early fruit fly embryo. These data are indispensable for formulating 
comprehensive and predictive models of animal development. Recent experimental 
data have indicated that membranes and not actin cytoskeleton dominate 
mechanical properties of the cellular boundaries in the early fruit fly embryo. 
The aim of the project is twofold: (1) to model mechanical response 
(deformation) of embryonic tissue to external calibrated mechanical 
manipulations, and (2) to leverage the model of embryonic tissue mechanics for 
simulating the dynamics of tissue shape changes during the early fruit fly 
development.


On the theoretical side, Pezeshkian lab has a unique expertise in simulating the 
dynamics of fluid membranes. On the experimental side, Doubrovinski lab has 
established a comprehensive toolbox for directly measuring mechanical responses 
of embryonic tissue to well-calibrated external force. A combination of these 
tools has the unique potential to deliver a genuinely quantitative mechanical 
model of tissue dynamics driving embryonic development.


Candidates must hold a Ph.D. degree. Experience in computational physics is 
required. A background in biophysics/developmental biology is a plus.


Information on our postdoctoral training program, benefits, and a virtual tour 
can be found at http://www.utsouthwestern.edu/postdocs.


Interested individuals should send a CV, statement of interests, and a list of 
three references to:


Konstantin Doubrovinski

Konstantin.Doubrovinski@utsouthwestern.edu https://doubrovinskilab.com/ 
Konstantin Doubrovinski, Ph.D. - Faculty Profile - UT Southwestern